Treatments affecting the rate of asbestos-induced mesotheliomas
نویسندگان
چکیده
منابع مشابه
Intermediate filament proteins in asbestos-induced mesotheliomas of the rat.
Abdominal diffuse malignant mesotheliomas develop in rats administered asbestos by the intraperitoneal route. A latency period of 6 to 24 months precedes tumor development; the biological and morphological features of these tumors resemble mesotheliomas in humans. Using one- and two-dimensional gel electrophoresis and immunoblotting, rat mesotheliomas (n = 24) were shown to express two classes ...
متن کاملChromosomal translocations with specific breakpoints in asbestos-induced rat mesotheliomas.
Cytogenetic analysis was conducted on cells of 15 rat mesotheliomas induced in rats by the i.p. inoculation of crocidolite or chrysotile asbestos. These tumor cells were diploid, triploid, or tetraploid. All tumor lines exhibited aneuploidy and marker chromosomes. Loss of at least one copy of the X chromosome was observed in each of the tumors analyzed, and loss of copies of chromosomes 8, 16, ...
متن کاملSoftware for Apportionment of Asbestos-Related Mesotheliomas
Patients with an asbestos-related mesothelioma may be legally entitled to financial compensation. In this context, a physician may be called upon to apportion the contribution of an asbestos containing product or facility where there was asbestos exposure in the development of that individual's mesothelioma. This task is mathematically not simple. It is a complex function of each and the entire...
متن کاملMesotheliomas--asbestos exposure and lung burden.
The assessment of asbestos fibres in the lungs at post mortem in groups of mesotheliomas, groups occupationally exposed to asbestos, and controls has shown that all these groups contain significant levels of asbestos as a lung burden. The amounts in each group are dependent on the degree of past exposure, being highest in those cases with a known or extrapolated occupational exposure, less in t...
متن کاملEnvironmental exposure to Libby Asbestos and mesotheliomas.
BACKGROUND Thirty-one cases of mesothelioma resulting from exposure to Libby Asbestos have been identified from Libby, Montana. Eleven cases not previously reported are the subject of this report. METHODS These cases are in non-occupationally exposed people, appearing to have resulted from exposure to contamination of the community, the surrounding forested area, and areas in proximity to the...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 1980
ISSN: 0007-0920,1532-1827
DOI: 10.1038/bjc.1980.169